Description

1-(3-Fluorobenzyl)-5,6-Dimethyl-2-Styryl-1H-1,3-Benzimidazole is a high-purity, advanced pharmaceutical intermediate belonging to the benzimidazole class of heterocyclic compounds. This compound matters for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting specific receptor pathways. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, including potential candidates in oncology and neurology.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the multi-step synthesis of complex drug molecules and investigational new drugs (INDs).
• Organic Light-Emitting Diode (OLED) Research: Used in the development of novel electron-transporting or host materials due to its conjugated styryl-benzimidazole structure.
• Agrochemical Research: Employed as a scaffold for creating new fungicides or plant growth regulators, leveraging the bioactivity of the benzimidazole core.
• Material Science: Investigated for use in the creation of specialty polymers and advanced organic semiconductors.
• Biochemical Research: Utilized as a fluorescent probe or a tag in bioconjugation chemistry for studying biological processes.
• Academic & Contract Research: A valuable compound for methodological studies in organic synthesis and heterocyclic chemistry at universities and CROs.

Basic Information

Product Name	1-(3-Fluorobenzyl)-5,6-Dimethyl-2-Styryl-1H-1,3-Benzimidazole
CAS No.	321433-03-8
Molecular Formula	C24H21FN2
Molecular Weight	356.44 g/mol
Synonyms	2-[(1E)-2-Phenylethenyl]-1-[(3-fluorophenyl)methyl]-5,6-dimethyl-1H-benzimidazole; 1-[(3-Fluorophenyl)methyl]-5,6-dimethyl-2-[(1E)-2-phenylethenyl]-1H-benzimidazole; 1-(3-Fluorobenzyl)-5,6-dimethyl-2-styrylbenzimidazole; 2-Styryl-1-(3-fluorobenzyl)-5,6-dimethylbenzimidazole; (E)-1-(3-Fluorobenzyl)-5,6-dimethyl-2-styryl-1H-benzimidazole
EINECS	Contact for details

Quality Control

Our 1-(3-Fluorobenzyl)-5,6-Dimethyl-2-Styryl-1H-1,3-Benzimidazole is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports compliance with cGMP and ISO standards for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flames. For long-term storage, consider inert gas purging to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.