Description

Methyl 4,5-Dihydronaphtho[1,2-B]Thiophene-2-Carboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its complex fused-ring structure. This compound matters as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system and oncological pathways. It is essential for research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents and high-value fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of complex drug candidates, especially those with naphthothiophene cores.
• Organic Light-Emitting Diode (OLED) Materials Research: Used in the development of novel electron-transport or host materials due to its fused aromatic-thiophene structure.
• Agrochemical Synthesis: Acts as a building block for creating new generation pesticides and herbicides with specific activity profiles.
• Material Science: Investigated for use in organic semiconductors and conductive polymers.
• Academic & Industrial R&D: Employed in methodological chemistry research and process development for scale-up synthesis.
• Ligand Synthesis: Used to prepare specialized ligands for catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	Methyl 4,5-Dihydronaphtho[1,2-B]Thiophene-2-Carboxylate
CAS No.	320423-96-9
Molecular Formula	C15H12O2S
Molecular Weight	256.32 g/mol
Synonyms	Methyl 4,5-dihydrobenzo[g]thieno[2,3-c]quinoline-3-carboxylate; 2-Carbomethoxy-4,5-dihydronaphtho[1,2-b]thiophene; Methyl 4,5-dihydronaphtho[1,2-b]thiophene-2-carboxylate; 4,5-Dihydronaphtho[1,2-b]thiophene-2-carboxylic acid methyl ester; Naphtho[1,2-b]thiophene-2-carboxylic acid, 4,5-dihydro-, methyl ester; 320423-96-9; Methyl 2,3-dihydro-1H-cyclopenta[b]naphthalene-5-carboxylate (related structural isomer)
EINECS	Contact for details

Quality Control

Our Methyl 4,5-Dihydronaphtho[1,2-B]Thiophene-2-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific client requirements for research or cGMP-grade material.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.