Description

4-Iodo-7-Azaindole is a high-value halogenated heterocyclic building block, specifically an iodo-substituted azaindole derivative. This compound is essential for medicinal chemistry research and development, serving as a versatile intermediate for constructing complex molecular architectures. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers engaged in the synthesis of kinase inhibitors and other biologically active small molecules.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of kinase inhibitors (e.g., JAK, ALK, EGFR inhibitors) and other targeted therapeutics.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization campaigns due to its halogen handle for cross-coupling reactions.
• Agrochemical Development: Serves as a building block for creating novel active ingredients with potential herbicidal or insecticidal properties.
• Material Science Precursor: Can be utilized in the development of organic electronic materials and ligands for catalytic systems.
• Bioconjugation & Probe Synthesis: The iodine atom allows for further functionalization, making it useful for creating biochemical probes and diagnostic agents.

Basic Information

Product Name	4-Iodo-7-Azaindole
CAS No.	319474-34-5
Molecular Formula	C7H5IN2
Molecular Weight	244.03 g/mol
Synonyms	4-Iodo-1H-pyrrolo[2,3-b]pyridine; 4-Iodo-7-azaindole; 1H-Pyrrolo[2,3-b]pyridine, 4-iodo-; 4-Iodo-1H-1,7-diazaindene; 4-Iodopyrrolo[2,3-b]pyridine; 7-Azaindole, 4-iodo-
EINECS	Contact for details

Quality Control

Our 4-Iodo-7-Azaindole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the stringent requirements of research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials. The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.