Description

8-Oxa-1-Azabicyclo[3.2.1]Octan-4-One,7-(1-Methylethyl)-,(1R,5R,7S)-Rel-(9Ci) is a high-purity, stereochemically defined bicyclic lactam compound that serves as a critical advanced pharmaceutical intermediate. Its value lies in its complex, rigid molecular framework, which is essential for constructing active pharmaceutical ingredients (APIs) with specific three-dimensional configurations. This product is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development and synthesis of novel therapeutic agents, particularly in areas requiring sophisticated chiral building blocks.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
• Organic Synthesis Research: Used in academic and industrial R&D for constructing novel heterocyclic compounds and exploring new chemical spaces.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies and lead optimization for new drug candidates.
• Asymmetric Synthesis: Serves as a precursor or template in catalytic asymmetric reactions due to its defined stereocenters.
• Process Chemistry Development: Used in scaling up synthetic routes from laboratory to pilot plant and commercial manufacturing scales.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	8-Oxa-1-Azabicyclo[3.2.1]Octan-4-One,7-(1-Methylethyl)-,(1R,5R,7S)-Rel-(9Ci)
CAS No.	319432-00-3
Molecular Formula	C9H15NO2
Molecular Weight	169.22 g/mol
Synonyms	(1R,5R,7S)-7-Isopropyl-8-oxa-1-azabicyclo[3.2.1]octan-4-one; rel-(1R,5R,7S)-7-(1-Methylethyl)-8-oxa-1-azabicyclo[3.2.1]octan-4-one; 7-Isopropyl-8-oxa-1-azabicyclo[3.2.1]octan-4-one (rel-(1R,5R,7S)-form); Bicyclic Lactam Intermediate; 8-Oxa-1-azabicyclo[3.2.1]octan-4-one derivative
EINECS	Contact for details

Quality Control

Our 8-Oxa-1-Azabicyclo[3.2.1]Octan-4-One,7-(1-Methylethyl)-,(1R,5R,7S)-Rel-(9Ci) is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including chiral purity verification and impurity profiling, to ensure it meets the high standards required for pharmaceutical development. Certificates of Analysis (COA) detailing identity, purity, and specific test results are provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.