Description

(6,7-Dimethoxy-3,4-Dihydro-1H-Isoquinolin-2-Yl)-Acetic Acid is a key synthetic intermediate in the production of complex pharmaceutical compounds. Its value lies in its role as a versatile building block for constructing molecules with specific biological activity, particularly within the isoquinoline alkaloid family. This compound is essential for research and development chemists and manufacturers in the pharmaceutical and fine chemical industries who require high-purity, reliable intermediates for API synthesis.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting neurological and cardiovascular systems.
• Alkaloid Synthesis: Serves as a core scaffold for the construction of complex isoquinoline-based natural products and their analogs for medicinal chemistry research.
• Chemical Research: Used as a specialized reagent in academic and industrial R&D for exploring new synthetic pathways and novel compound libraries.
• Fine Chemical Production: Employed in the manufacture of high-value specialty chemicals used in advanced material science and agrochemical research.

Basic Information

Product Name	(6,7-Dimethoxy-3,4-Dihydro-1H-Isoquinolin-2-Yl)-Acetic Acid
CAS No.	318465-71-3
Molecular Formula	C₁₃H₁₇NO₄
Molecular Weight	251.28 g/mol
Synonyms	2-(6,7-Dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)acetic acid; 2-(6,7-Dimethoxy-1,2,3,4-tetrahydroisoquinolin-2-yl)acetic acid; (6,7-Dimethoxy-1,2,3,4-tetrahydroisoquinolin-2-yl)acetic acid; 6,7-Dimethoxy-1,2,3,4-tetrahydroisoquinoline-2-acetic acid; Dihydroisoquinoline acetic acid derivative; TIQAA derivative; Contact for EINECS details.

Quality Control

Our (6,7-Dimethoxy-3,4-Dihydro-1H-Isoquinolin-2-Yl)-Acetic Acid is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure it meets the high-purity standards required for pharmaceutical intermediate applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.