Description

8-Oxo-5,6,7,8-Tetrahydro-Indolizine-5-Carboxylic Acid Methyl Ester is a high-purity, advanced pharmaceutical intermediate crucial for modern synthetic chemistry. This compound serves as a versatile and sophisticated building block for the development of novel active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for complex synthesis and process development.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and production of complex heterocyclic drug candidates and APIs.
• Organic Synthesis Building Block: Used in multi-step synthesis for constructing indolizine and fused ring systems with high structural complexity.
• Medicinal Chemistry Research: Employed in lead optimization and structure-activity relationship (SAR) studies for new therapeutic agents.
• Agrochemical Development: Serves as an intermediate in the synthesis of novel crop protection agents and pesticides.
• Academic & Industrial R&D: A valuable reagent for methodological development and exploring new chemical transformations in laboratory settings.

Basic Information

Product Name	8-Oxo-5,6,7,8-Tetrahydro-Indolizine-5-Carboxylic Acid Methyl Ester
CAS No.	318247-33-5
Molecular Formula	C11H13NO3
Molecular Weight	207.23 g/mol
Synonyms	Methyl 8-oxo-5,6,7,8-tetrahydroindolizine-5-carboxylate; 5,6,7,8-Tetrahydro-8-oxoindolizine-5-carboxylic acid methyl ester; 8-Oxo-5,6,7,8-tetrahydroindolizine-5-carboxylic acid methyl ester; Indolizine-5-carboxylic acid, 5,6,7,8-tetrahydro-8-oxo-, methyl ester; Methyl 5,6,7,8-tetrahydro-8-oxoindolizine-5-carboxylate
EINECS	Contact for details

Quality Control

Our 8-Oxo-5,6,7,8-Tetrahydro-Indolizine-5-Carboxylic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents, strong acids, and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.