Description

3-(1-Amino-Ethyl)-Indole-1-Carboxylic Acid tert-Butyl Ester is a high-purity, protected indole derivative that serves as a critical chiral building block in advanced organic synthesis. This compound is valued for its role in constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and bioactive compounds. It is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors for process development and scale-up activities.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Development: Used in the research and production of advanced pesticides and herbicides requiring specific stereochemistry.
• Peptidomimetics & Bioconjugation: Serves as a protected amino acid analog for constructing peptide-like molecules and bioconjugates.
• Asymmetric Catalysis Research: Employed as a substrate or ligand precursor in the development of new catalytic systems.
• Material Science: Potential monomer or precursor for specialty polymers and functional organic materials.
• Academic & Process Chemistry: A versatile reagent for methodological studies and scalable route development in academic and industrial R&D labs.

Basic Information

Product Name	3-(1-Amino-Ethyl)-Indole-1-Carboxylic Acid tert-Butyl Ester
CAS No.	317830-77-6
Molecular Formula	C15H20N2O2
Molecular Weight	260.33 g/mol
Synonyms	1H-Indole-1-carboxylic acid, 3-(1-aminoethyl)-, 1,1-dimethylethyl ester; tert-Butyl 3-(1-aminoethyl)-1H-indole-1-carboxylate; 3-(1-Aminoethyl)indole-1-carboxylic acid tert-butyl ester; 1-Boc-3-(1-aminoethyl)indole; N-Boc-3-(1-aminoethyl)indole; 3-(α-Aminoethyl)indole N-Boc derivative; (R/S)-3-(1-Aminoethyl)-1H-indole-1-carboxylic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our 3-(1-Amino-Ethyl)-Indole-1-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) with full traceability are available upon request, and we can support custom specifications to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (or as specified)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.