Description

Ethyl 5-[2-(Methoxycarbonyl)-3-thienyl]-4,6-dioxo-1,3a,4,5,6,6a-hexahydropyrrolo[3,4-c]pyrazole-3-carboxylate is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of complex active pharmaceutical ingredients (APIs). This compound is critical for research and development in medicinal chemistry, offering a sophisticated heterocyclic scaffold for creating novel therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing new drugs, particularly in areas requiring complex fused-ring systems.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel APIs, especially those targeting central nervous system (CNS) disorders or anti-inflammatory pathways.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Heterocyclic Compound Synthesis: Serves as a precursor for the development of more complex polycyclic compounds with potential biological activity.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and scale-up of complex molecules for clinical trials.
• Academic Research: Utilized in university and institutional labs for studying novel organic reactions and synthesizing new chemical entities.

Basic Information

Product Name	Ethyl 5-[2-(Methoxycarbonyl)-3-thienyl]-4,6-dioxo-1,3a,4,5,6,6a-hexahydropyrrolo[3,4-c]pyrazole-3-carboxylate
CAS No.	317821-62-8
Molecular Formula	C15H15N3O6S
Molecular Weight	365.36 g/mol
Synonyms	Ethyl 5-(2-methoxycarbonyl-3-thienyl)-4,6-dioxo-1,3a,4,5,6,6a-hexahydropyrrolo[3,4-c]pyrazole-3-carboxylate; 1,3a,4,5,6,6a-Hexahydro-5-[2-(methoxycarbonyl)-3-thienyl]-4,6-dioxopyrrolo[3,4-c]pyrazole-3-carboxylic acid ethyl ester; Pyrrolo[3,4-c]pyrazole-3-carboxylic acid, 1,3a,4,5,6,6a-hexahydro-5-[2-(methoxycarbonyl)-3-thienyl]-4,6-dioxo-, ethyl ester; Ethyl 1,3a,4,5,6,6a-hexahydro-5-(2-methoxycarbonyl-3-thienyl)-4,6-dioxopyrrolo[3,4-c]pyrazole-3-carboxylate; CAS 317821-62-8.
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Quality Control

Our Ethyl 5-[2-(Methoxycarbonyl)-3-thienyl]-4,6-dioxo-1,3a,4,5,6,6a-hexahydropyrrolo[3,4-c]pyrazole-3-carboxylate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for pharmaceutical research. All products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound may be moisture-sensitive; keep the container tightly sealed in a dry environment. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.