Description

2-Amino-4-(4-Ethoxy-Phenyl)Thiophene-3-Carboxylic Ethyl Ester is a high-purity, specialized organic building block of significant interest in advanced chemical synthesis. Its molecular structure, featuring both amino and ester functional groups on a thiophene core, makes it a versatile intermediate for constructing complex heterocyclic systems. This compound is primarily sought after by research institutions and pharmaceutical development teams for the creation of novel active pharmaceutical ingredients (APIs) and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic scaffold for bioactivity.
• Material Science: Serves as a monomer or building block for advanced polymers, organic semiconductors, and non-linear optical (NLO) materials.
• Dye & Pigment Synthesis: Employed in the production of specialized dyes and pigments due to the chromophoric properties of the thiophene ring.
• Academic & Contract Research: Essential for medicinal chemistry programs and structure-activity relationship (SAR) studies in university and CRO laboratories.
• Chemical Library Development: Used by combinatorial chemistry groups to create diverse compound libraries for high-throughput screening.

Basic Information

Product Name	2-Amino-4-(4-Ethoxy-Phenyl)Thiophene-3-Carboxylic Ethyl Ester
CAS No.	315684-37-8
Molecular Formula	C15H17NO3S
Molecular Weight	291.36 g/mol
Synonyms	Ethyl 2-Amino-4-(4-ethoxyphenyl)thiophene-3-carboxylate; 4-(4-Ethoxyphenyl)-2-aminothiophene-3-carboxylic Acid Ethyl Ester; 2-Amino-4-(p-ethoxyphenyl)thiophene-3-carboxylic Acid Ethyl Ester; 3-Thiophenecarboxylic Acid, 2-Amino-4-(4-ethoxyphenyl)-, Ethyl Ester; ATCE; AE-TCE; 315684-37-8
EINECS	Contact for details

Quality Control

Every batch of 2-Amino-4-(4-Ethoxy-Phenyl)Thiophene-3-Carboxylic Ethyl Ester is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical characteristics is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.