Description

Methyl (E)-2-(2-Cyano-3-(Thiophen-2-Yl)Acrylamido)-4,5,6,7-Tetrahydrobenzo[B]Thiophene-3-Carboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is of significant commercial interest for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought by research institutions and manufacturers in the pharmaceutical and agrochemical sectors engaged in developing new therapeutic agents and crop protection solutions.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Research: Serves as a core scaffold for developing new-generation herbicides and insecticides with specific modes of action.
• Organic Synthesis Building Block: Used in academic and industrial R&D for constructing complex fused thiophene and benzo[b]thiophene derivatives.
• Material Science Precursor: Potential application in the development of organic semiconductors and non-linear optical (NLO) materials due to its conjugated system.
• Chemical Biology Probe: Utilized in medicinal chemistry for structure-activity relationship (SAR) studies and biological target identification.

Basic Information

Product Name	Methyl (E)-2-(2-Cyano-3-(Thiophen-2-Yl)Acrylamido)-4,5,6,7-Tetrahydrobenzo[B]Thiophene-3-Carboxylate
CAS No.	315241-54-4
Molecular Formula	C₁₈H₁₆N₂O₃S₂
Molecular Weight	372.46 g/mol
Synonyms	Methyl 2-[(1E)-2-cyano-3-(2-thienyl)-2-propenamido]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate; (E)-Methyl 2-(2-cyano-3-(thiophen-2-yl)acrylamido)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylate; 315241-54-4; Tetrahydrobenzo[b]thiophene-3-carboxylate derivative; 2-Cyano-3-(2-thienyl)acrylamido tetrahydrobenzothiophene ester
EINECS	Contact for details

Quality Control

Our production of Methyl (E)-2-(2-Cyano-3-(Thiophen-2-Yl)Acrylamido)-4,5,6,7-Tetrahydrobenzo[B]Thiophene-3-Carboxylate adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and MS, to ensure it meets the exacting standards required for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with each shipment, guaranteeing traceability and consistent batch-to-batch purity.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.