Description

7,8-Dimethoxy-3-phenoxy-2-(trifluoromethyl)-4H-chromen-4-one is a specialized chromenone derivative, a high-value chemical intermediate prized for its unique trifluoromethyl and phenoxy substituents. This compound matters for its role in facilitating complex molecular synthesis, particularly in the development of advanced materials and active pharmaceutical ingredients (APIs). It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material science industries seeking to incorporate fluorinated motifs into novel compounds.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or requiring fluorinated structures for enhanced metabolic stability and bioavailability.
• Agrochemical Research: Serves as a precursor in developing new-generation pesticides and herbicides, where the trifluoromethyl group can impart improved lipophilicity and biological activity.
• Material Science: Used in the synthesis of organic electronic materials, such as components for OLEDs (Organic Light-Emitting Diodes) or fluorinated polymers, due to its electron-deficient aromatic system.
• Chemical Biology Probe Development: Employed as a scaffold for creating fluorescent tags or enzyme inhibitors used in biochemical assays and diagnostic research.
• Academic & Contract Research: A valuable reagent for universities and CROs (Contract Research Organizations) conducting fundamental research in synthetic organic chemistry and medicinal chemistry.
• Fine Chemical Synthesis: Acts as a versatile intermediate for the custom synthesis of complex, high-value specialty chemicals for various industrial applications.

Basic Information

Item	Details
Product Name	7,8-Dimethoxy-3-phenoxy-2-(trifluoromethyl)-4H-chromen-4-one
CAS No.	315233-82-0
Molecular Formula	C18H13F3O5
Molecular Weight	366.29 g/mol
Synonyms	2-(Trifluoromethyl)-3-phenoxy-7,8-dimethoxy-4H-chromen-4-one; 7,8-Dimethoxy-3-phenoxy-2-trifluoromethylchromone; 4H-1-Benzopyran-4-one, 7,8-dimethoxy-3-phenoxy-2-(trifluoromethyl)-; Chromen-4-one, 7,8-dimethoxy-3-phenoxy-2-(trifluoromethyl)-; 3-Phenoxy-7,8-dimethoxy-2-(trifluoromethyl)chromone
EINECS	Contact for details

Quality Control

Our 7,8-Dimethoxy-3-phenoxy-2-(trifluoromethyl)-4H-chromen-4-one is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports compliance with cGMP and ISO standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to minimize exposure to atmospheric humidity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.