Description

Benzenethiol, 2-Fluoro-4-Nitro- is a specialized aromatic thiol derivative characterized by its unique combination of a nitro group and a fluorine substituent. This compound serves as a valuable and versatile building block in advanced organic synthesis, particularly for the development of complex molecules in pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists working on novel active ingredients, functional materials, and ligand systems.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and pesticides, leveraging the bioactivity of the nitro and thiol functionalities.
• Ligand and Catalyst Development: Acts as a precursor for creating specialized ligands used in transition metal catalysis and coordination chemistry.
• Material Science Research: Employed in the synthesis of functionalized polymers, liquid crystals, and advanced organic electronic materials.
• Chemical Derivatization: Useful for introducing sulfur-containing moieties into complex molecular architectures for structure-activity relationship (SAR) studies.

Basic Information

Product Name	Benzenethiol, 2-Fluoro-4-Nitro-
CAS No.	315228-67-2
Molecular Formula	C6H4FNO2S
Molecular Weight	173.16 g/mol
Synonyms	2-Fluoro-4-nitrobenzenethiol; 2-Fluoro-4-nitrothiophenol; 1-Fluoro-2-mercapto-5-nitrobenzene; 4-Nitro-2-fluorobenzenethiol; 2-Fluoro-4-nitro-phenyl mercaptan; (2-Fluoro-4-nitrophenyl)thiol; 2-Fluoro-4-nitrothioanisole (precursor related); SCHEMBL12345678 (example research catalog ID)
EINECS	Contact for details

Quality Control

Every batch of Benzenethiol, 2-Fluoro-4-Nitro- is produced and tested under strict quality management protocols to ensure consistency and reliability for research and development purposes. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as purity, identity, and impurity profiles. Our quality systems are designed to support cGMP compliance for pharmaceutical applications, and we can accommodate custom purity specifications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its properties, this material is easily oxidized and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and during sampling to maintain stability and purity. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.