Description

Methyl 5-Benzyl-4-Methyl-2-[(3-Methylbenzoyl)Amino]-3-Thiophenecarboxylate is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound matters for its critical role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular architectures. Pharmaceutical R&D laboratories and fine chemical manufacturers need this precise intermediate to ensure the integrity and scalability of their synthetic routes, enabling the development of next-generation medications.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the multi-step synthesis of proprietary drug candidates and novel chemical entities.
• Organic Synthesis Building Block: Used in research and development for constructing complex thiophene-containing molecules with potential biological activity.
• Agrochemical Research: Acts as a key intermediate in the development of new crop protection agents and pesticides that leverage its specific heterocyclic core.
• Material Science Research: Investigated for the development of specialty polymers or organic electronic materials due to its conjugated thiophene system.
• Contract Manufacturing (CMO): Supplied to contract development and manufacturing organizations (CDMOs) for custom synthesis projects under cGMP conditions.
• Academic & Institutional Research: Utilized in university and institutional labs for methodological studies in heterocyclic and medicinal chemistry.

Basic Information

Product Name	Methyl 5-Benzyl-4-Methyl-2-[(3-Methylbenzoyl)Amino]-3-Thiophenecarboxylate
CAS No.	314283-56-2
Molecular Formula	C22H21NO3S
Molecular Weight	379.47 g/mol
Synonyms	Methyl 2-[(3-methylbenzoyl)amino]-5-benzyl-4-methyl-3-thiophenecarboxylate; 3-Thiophenecarboxylic acid, 2-[(3-methylbenzoyl)amino]-5-benzyl-4-methyl-, methyl ester; 5-Benzyl-4-methyl-2-(3-methylbenzamido)thiophene-3-carboxylic acid methyl ester; Methyl 5-benzyl-4-methyl-2-(m-toluamido)thiophene-3-carboxylate; 314283-56-2; CAS 314283-56-2
EINECS	Contact for details

Quality Control

Our Methyl 5-Benzyl-4-Methyl-2-[(3-Methylbenzoyl)Amino]-3-Thiophenecarboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters. Our production can be aligned with cGMP guidelines for pharmaceutical applications upon request, ensuring traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.