Description

2-[(1H-Indol-3-Ylmethylene)Amino]-5-Methylphenol is a Schiff base derivative, a versatile organic compound formed by the condensation of an indole aldehyde and an aminophenol. This compound matters for its role as a key intermediate in the synthesis of more complex heterocyclic molecules and as a potential ligand in coordination chemistry. It is needed by research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials. The CAS number for this product is 314281-75-9.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of novel drug candidates, particularly those targeting neurological or oncological pathways.
• Agrochemical Research: Used in the development of new pesticides and herbicides due to its heterocyclic structure which can interact with biological targets.
• Coordination Chemistry & Catalysis: Acts as a potential ligand for metal ions (e.g., Cu, Zn, Fe) to form complexes with applications in catalysis or material science.
• Organic Synthesis Building Block: Employed in academic and industrial R&D for constructing complex indole-containing frameworks.
• Dye & Pigment Precursor: Its conjugated structure makes it a candidate for developing new organic colorants and functional dyes.
• Analytical Reagent: Can be utilized as a chelating agent in spectrophotometric methods for metal ion detection.

Basic Information

Product Name	2-[(1H-Indol-3-Ylmethylene)Amino]-5-Methylphenol
CAS No.	314281-75-9
Molecular Formula	C₁₆H₁₄N₂O
Molecular Weight	250.30 g/mol
Synonyms	5-Methyl-2-[(1H-indol-3-ylmethylene)amino]phenol; 2-[(1H-Indol-3-ylmethylidene)amino]-5-methylphenol; 2-[(Indol-3-ylmethylene)amino]-5-methylphenol; N-(5-Methyl-2-hydroxyphenyl)-1H-indole-3-carboxaldimine; Schiff base of 3-formylindole and 2-amino-5-methylphenol; Indole-3-carboxaldehyde-(5-methyl-2-hydroxyanil) (E)-2-((1H-Indol-3-ylmethylene)amino)-5-methylphenol
EINECS	Contact for details

Quality Control

Our 2-[(1H-Indol-3-Ylmethylene)Amino]-5-Methylphenol is manufactured under strict quality protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, physical characteristics, and test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is easily oxidized (store under inert atmosphere) and is light-sensitive (store away from light). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.