Description

2-(3-Oxo-3,4-Dihydro-2H-Benzo[B][1,4]Thiazin-2-Yl)-n-(3-(Trifluoromethyl)Phenyl)Acetamide is a high-purity, advanced pharmaceutical intermediate characterized by its unique heterocyclic benzo[b][1,4]thiazine core and trifluoromethylphenyl moiety. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of novel therapeutic agents with enhanced metabolic stability and bioavailability. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of new chemical entities, particularly for central nervous system (CNS) and anti-inflammatory targets.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting neurological and inflammatory pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to explore and optimize biological activity profiles.
• Active Pharmaceutical Ingredient (API) Development: Serves as a core scaffold for the development of potential new APIs.
• Biochemical Research: Employed as a tool compound in biochemical assays to study enzyme inhibition or receptor binding.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.

Basic Information

Product Name	2-(3-Oxo-3,4-Dihydro-2H-Benzo[B][1,4]Thiazin-2-Yl)-n-(3-(Trifluoromethyl)Phenyl)Acetamide
CAS No.	314278-89-2
Molecular Formula	C₁₇H₁₃F₃N₂O₂S
Molecular Weight	366.36 g/mol
Synonyms	2-(3-Oxo-4H-1,4-benzothiazin-2-yl)-N-[3-(trifluoromethyl)phenyl]acetamide; 2-(3-Oxo-3,4-dihydro-2H-1,4-benzothiazin-2-yl)-N-(3-(trifluoromethyl)phenyl)acetamide; N-(3-(Trifluoromethyl)phenyl)-2-(3-oxo-3,4-dihydro-2H-benzo[b][1,4]thiazin-2-yl)acetamide; 314278-89-2; Acetamide, 2-(3-oxo-3,4-dihydro-2H-1,4-benzothiazin-2-yl)-N-[3-(trifluoromethyl)phenyl]-
EINECS	Contact for details

Quality Control

Our 2-(3-Oxo-3,4-Dihydro-2H-Benzo[B][1,4]Thiazin-2-Yl)-n-(3-(Trifluoromethyl)Phenyl)Acetamide is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes rigorous analytical testing, including HPLC for assay and impurity profiling, to meet the stringent requirements of pharmaceutical R&D. Certificates of Analysis (COA) detailing identity, purity, and related substances are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to ensure stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any single impurity ≤ 0.5%; Total impurities ≤ 1.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.