Description

2-Thiazolepropanenitrile, -Bta--Oxo- is a specialized heterocyclic nitrile building block of significant interest in advanced organic synthesis. Its unique molecular architecture, featuring both a thiazole ring and a reactive nitrile group, makes it a valuable precursor for constructing complex pharmacophores and functional materials. This high-purity intermediate is primarily sought by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly those targeting neurological and metabolic disorders.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the thiazole moiety contributes to biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating novel ligands in coordination chemistry and catalysts for asymmetric synthesis.
• Material Science Research: Employed in the development of organic semiconductors, conductive polymers, and other functional organic materials.
• Chemical Biology Probes: Utilized to build molecular probes for studying enzyme mechanisms and cellular processes.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis projects requiring complex heterocyclic frameworks.

Basic Information

Product Name	2-Thiazolepropanenitrile, -Bta--Oxo-
CAS No.	314268-27-4
Molecular Formula	C6H6N2OS
Molecular Weight	154.19 g/mol
Synonyms	2-(3-Oxobutyl)thiazole-4-carbonitrile; 4-Cyano-2-(3-oxobutyl)thiazole; 2-(3-Oxobutyl)-4-thiazolecarbonitrile; 4-Thiazolecarbonitrile, 2-(3-oxobutyl)-; β-Oxo-2-thiazolepropanenitrile; 2-Thiazolepropanenitrile, β-oxo-; (4-Cyano-2-thiazolyl)acetone
EINECS	Contact for details

Quality Control

Every batch of 2-Thiazolepropanenitrile, -Bta--Oxo- is manufactured and tested under a strict quality management system to ensure consistency and reliability for your critical syntheses. We provide comprehensive analytical data, including HPLC purity, identity confirmation by IR and NMR spectroscopy, and residual solvent analysis. A Certificate of Analysis (COA) documenting all release specifications is available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.