Description

4H-Cyclohepta[B]Thiophene-3-Carboxylic Acid, 2-[(3-Chloro-1-Oxopropyl)Amino]-5,6,7,8-Tetrahydro-, Ethyl Ester is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in research and development targeting specific therapeutic areas. It is primarily required by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the production of complex organic molecules. The product, identified by CAS NO 314244-45-6, is supplied under stringent quality control to ensure batch-to-batch consistency for demanding synthetic applications.

Application

This specialized intermediate serves as a key building block in sophisticated organic synthesis. Its primary applications include:

• Pharmaceutical Research & Development: As a critical precursor in the synthesis of novel drug candidates, particularly those with heterocyclic cores.
• Active Pharmaceutical Ingredient (API) Manufacturing: Used in the scaled-up production of complex target molecules for clinical trials and commercial supply.
• Medicinal Chemistry: Enabling structure-activity relationship (SAR) studies and lead optimization processes in drug discovery programs.
• Fine Chemical Synthesis: Serving as a starting material or intermediate for the production of other high-value, complex organic compounds.
• Contract Research Organizations (CROs) & CDMOs: Supplying process development and custom synthesis services for the global pharmaceutical industry.

Basic Information

Product Name	4H-Cyclohepta[B]Thiophene-3-Carboxylic Acid, 2-[(3-Chloro-1-Oxopropyl)Amino]-5,6,7,8-Tetrahydro-, Ethyl Ester
CAS No.	314244-45-6
Molecular Formula	C15H20ClNO3S
Molecular Weight	329.84 g/mol
Synonyms	Ethyl 2-[(3-chloropropanoyl)amino]-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carboxylate; 2-[(3-Chloro-1-oxopropyl)amino]-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carboxylic acid ethyl ester; 4H-Cyclohepta[b]thiophene-3-carboxylic acid, 2-[(3-chloro-1-oxopropyl)amino]-5,6,7,8-tetrahydro-, ethyl ester; UNII-7K1JZW805N; 7K1JZW805N; SCHEMBL218062; AOB31117; BCP31063.
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to confirm identity and purity. We provide a detailed Certificate of Analysis (COA) with each shipment, ensuring full traceability and compliance with your internal specifications and the standards expected for pharmaceutical R&D. Our commitment to cGMP principles in manufacturing guarantees the reliability and consistency required for critical synthetic pathways.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.