Description

Methyl 7-Bromo-2,3-Dihydro-1H-1-Benzazepine-4-Carboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its benzazepine core structure and bromo-substituent. This compound is a critical building block in modern organic synthesis, enabling the development of novel active pharmaceutical ingredients (APIs) with targeted therapeutic effects. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of central nervous system (CNS) agents and other specialized drug candidates.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of novel drug candidates, particularly those targeting neurological pathways.
• Organic Synthesis Building Block: Used in complex multi-step syntheses to construct benzazepine-based molecular frameworks for medicinal chemistry programs.
• Research & Development (R&D): Essential for academic and industrial R&D labs exploring new chemical entities and structure-activity relationships (SAR).
• Process Chemistry: Employed in route scouting and scale-up studies for the efficient production of target molecules in pilot and commercial-scale manufacturing.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	Methyl 7-Bromo-2,3-Dihydro-1H-1-Benzazepine-4-Carboxylate
CAS No.	313724-44-6
Molecular Formula	C₁₃H₁₄BrNO₂
Molecular Weight	296.16 g/mol
Synonyms	7-Bromo-2,3-dihydro-1H-1-benzazepine-4-carboxylic acid methyl ester; Methyl 7-bromo-2,3-dihydro-1H-1-benzazepine-4-carboxylate; 1H-1-Benzazepine-4-carboxylic acid, 7-bromo-2,3-dihydro-, methyl ester; 313724-44-6; 7-Bromo-2,3-dihydro-1H-benzo[b]azepine-4-carboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 7-Bromo-2,3-Dihydro-1H-1-Benzazepine-4-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.