Description

Carbamic Acid, n-[(1S)-2-[4-[(2-Methyl-4-Thiazolyl)Methoxy]Phenyl]-1-(2S)-2-Oxiranylethyl]-, 1,1-Dimethylethyl Ester is a sophisticated chiral organic compound featuring a thiazole and an epoxide moiety, serving as a critical advanced pharmaceutical intermediate (API intermediate). Its complex structure is designed for high-value synthesis, primarily in the development of targeted therapeutic agents. This compound is essential for research institutions and pharmaceutical manufacturers engaged in the synthesis of novel drug candidates, particularly in areas requiring specific stereochemistry and functional group compatibility.

Application

• Key Intermediate in Pharmaceutical Synthesis: Serves as a crucial building block for the research and development of new active pharmaceutical ingredients (APIs).
• Protease Inhibitor Research: Used in the synthesis pathway for potential protease inhibitor candidates, leveraging its specific stereocenters and reactive epoxide group.
• Antiviral Drug Development: Applied in the exploratory synthesis of compounds targeting viral enzymes, given the structural relevance of the thiazole ring.
• Custom Organic Synthesis: Employed by contract research organizations (CROs) and fine chemical suppliers for bespoke, multi-step synthetic routes.
• Chemical Biology & Medicinal Chemistry: Utilized as a probe or precursor in studying enzyme-substrate interactions and structure-activity relationships (SAR).
• Process Chemistry & Scale-Up: Acts as a benchmark material for developing and optimizing scalable, GMP-compliant manufacturing processes for complex molecules.

Basic Information

Product Name	Carbamic Acid, n-[(1S)-2-[4-[(2-Methyl-4-Thiazolyl)Methoxy]Phenyl]-1-(2S)-2-Oxiranylethyl]-, 1,1-Dimethylethyl Ester
CAS No.	313680-92-1
Molecular Formula	C20H26N2O4S
Molecular Weight	390.50 g/mol
Synonyms	tert-Butyl N-[(1S)-2-[4-[(2-methyl-1,3-thiazol-4-yl)methoxy]phenyl]-1-[(2S)-oxiran-2-yl]ethyl]carbamate; (2S)-1-[(2S)-2-[(tert-Butoxycarbonyl)amino]-3-[4-[(2-methyl-4-thiazolyl)methoxy]phenyl]propyl]oxirane; BOC-Protected Amino Epoxide Intermediate; (S,S)-BOC-Amino Thiazole Phenyl Epoxide; CAS 313680-92-1; 1,1-Dimethylethyl N-[(1S)-2-[4-[(2-methyl-4-thiazolyl)methoxy]phenyl]-1-[(2S)-2-oxiranyl]ethyl]carbamate
EINECS	Contact for details

Quality Control

Our production of this high-purity intermediate adheres to strict quality management systems. Every batch is characterized and verified using advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry to ensure identity, purity, and chiral integrity. Certificates of Analysis (COA) detailing all critical parameters are provided with each shipment. We support development and commercial projects with specifications that can meet the requirements for GMP starting material and non-GMP research use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture uptake, which can affect stability and handling properties. For long-term storage beyond one year, consider storage at 2-8°C under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.