Description

1-Bromo-2-Chloro-4-Ethoxybenzene is a high-purity halogenated aromatic ether building block of significant importance in advanced organic synthesis. This compound matters as a versatile intermediate for constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and specialty agrochemicals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries seeking to introduce specific halogen and alkoxy functionalities into target molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, especially in medicinal chemistry programs targeting CNS and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides, where the ethoxy and halogen groups contribute to biological activity.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for creating specialized aromatic cores in electronic and display materials.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl structures.
• Functional Dye Chemistry: Employed in the synthesis of halogenated chromophores and photoactive compounds.
• Polymer Modification: Acts as a monomer or functionalization agent for engineering polymers with specific thermal or optical properties.
• Chemical Research & Development: A valuable reagent for method development and exploring new synthetic pathways in academic and industrial labs.

Basic Information

Product Name	1-Bromo-2-Chloro-4-Ethoxybenzene
CAS No.	313545-43-6
Molecular Formula	C8H8BrClO
Molecular Weight	235.51 g/mol
Synonyms	2-Chloro-1-bromo-4-ethoxybenzene; 4-Ethoxy-1-bromo-2-chlorobenzene; 1-Bromo-2-chloro-4-ethoxy-benzene; Benzene, 1-bromo-2-chloro-4-ethoxy-; 4-Ethoxy-2-chlorobromobenzene; 2-Chloro-4-ethoxybromobenzene; p-Ethoxy-o-chlorobromobenzene
EINECS	Contact for details

Quality Control

Our 1-Bromo-2-Chloro-4-Ethoxybenzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Purity (GC)	≥97.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.