Description

Ethyl 2-(3-Nitrobenzamido)-5,6-Dihydro-4H-Cyclopenta[B]Thiophene-3-Carboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is of significant value in medicinal chemistry for the research and development of novel therapeutic agents, particularly due to its fused thiophene and cyclopentane core. It is primarily sought by R&D laboratories and pharmaceutical manufacturers engaged in the synthesis of new chemical entities targeting a range of biological pathways. The product is supplied with a focus on consistent quality and reliable supply chain integrity for global research and production needs.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the multi-step synthesis of potential drug candidates, especially those exploring thiophene-based pharmacophores.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes within academic and industrial R&D settings.
• Organic Synthesis Reference Standard: Employed as a pure reference material for analytical method development and validation in QC laboratories.
• Biochemical Probe Development: Potential use in the development of chemical probes for studying enzyme inhibition or receptor binding mechanisms.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP or non-GMP conditions.

Basic Information

Product Name	Ethyl 2-(3-Nitrobenzamido)-5,6-Dihydro-4H-Cyclopenta[B]Thiophene-3-Carboxylate
CAS No.	313262-44-1
Molecular Formula	C17H16N2O5S
Molecular Weight	360.39 g/mol
Synonyms	Ethyl 2-[(3-nitrobenzoyl)amino]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate; 2-(3-Nitrobenzamido)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylic acid ethyl ester; 4,5,6,7-Tetrahydro-2-[[(3-nitrophenyl)carbonyl]amino]benzo[b]thiophene-3-carboxylic acid ethyl ester; 313262-44-1; Ethyl 2-(3-nitrobenzamido)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate; AI3-52300; SCHEMBL2180771; ZINC000004143756.
EINECS	Contact for details

Quality Control

Our Ethyl 2-(3-Nitrobenzamido)-5,6-Dihydro-4H-Cyclopenta[B]Thiophene-3-Carboxylate is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all test results and specifications is provided with every shipment. We can support development projects requiring compliance with various pharmacopeial or internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.