Description

(-)-1-(Chloro-Methylamino-Phenyl)-1,2,3,4-Tetra-H-Isoquinoline (-)-Tartrate, 98 CAS NO 313222-93-4 is a high-purity, chiral organic compound offered at 98% purity, serving as a critical building block in advanced chemical synthesis. This product matters for its role as a sophisticated intermediate in the development of active pharmaceutical ingredients (APIs) and other fine chemicals where stereochemical control is paramount. It is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for process development and scale-up activities.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel therapeutic agents, particularly in central nervous system (CNS) and cardiovascular drug candidates.
• Asymmetric Synthesis: Employed in catalytic and stoichiometric asymmetric reactions to construct complex molecular architectures with high enantiomeric purity.
• Agrochemical Research: Used in the synthesis of advanced, biologically active compounds for crop protection and pest management.
• Chemical Biology & Probe Development: Serves as a scaffold for creating molecular probes to study biological pathways and enzyme functions.
• Process Chemistry & Scale-Up: Utilized in pilot plant and manufacturing settings for the production of kilogram to multi-kilogram quantities of target molecules.
• Academic & Contract Research: A valuable reagent for universities and CROs (Contract Research Organizations) engaged in synthetic methodology and medicinal chemistry projects.

Basic Information

Item	Details
Product Name	(-)-1-(Chloro-Methylamino-Phenyl)-1,2,3,4-Tetra-H-Isoquinoline (-)-Tartrate, 98
CAS No.	313222-93-4
Molecular Formula	C21H21ClN2O6
Molecular Weight	432.86 g/mol
Synonyms	(-)-1-[(4-Chlorophenyl)methylamino]-1,2,3,4-tetrahydroisoquinoline L-tartrate; (R)-1-[(4-Chlorobenzyl)amino]-1,2,3,4-tetrahydroisoquinoline hydrogen L-tartrate; 1-[(4-Chlorophenyl)methylamino]-1,2,3,4-tetrahydroisoquinoline (2R,3R)-2,3-dihydroxybutanedioate; (-)-CMPTI Tartrate; 313222-93-4; 4-Chloro-N-[(1R)-1,2,3,4-tetrahydroisoquinolin-1-yl]methyl]benzenamine (2R,3R)-2,3-dihydroxybutanedioate
EINECS	Contact for details

Quality Control

Our (-)-1-(Chloro-Methylamino-Phenyl)-1,2,3,4-Tetra-H-Isoquinoline (-)-Tartrate is produced under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets the specified 98% minimum purity. Certificates of Analysis (COA) detailing identity, assay, and impurity profiles are available upon request and are essential for regulatory submissions in target industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); therefore, the container should be kept tightly sealed in a dry environment. For long-term storage, consider conditions under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.