Description

1-(3-Dimethylamino-2-Hydroxy-Propyl)-1H-Indole-3-Carbaldehyde is a versatile indole derivative featuring a functionalized side chain, making it a valuable building block in advanced organic synthesis. This compound is critical for research and development in pharmaceutical chemistry, where it serves as a key precursor for creating novel bioactive molecules. It is primarily needed by fine chemical manufacturers, pharmaceutical R&D laboratories, and academic institutions focused on medicinal chemistry and heterocyclic compound development.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting neurological and oncological pathways.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and the development of new pharmacophores.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of specialty chemicals, agrochemicals, and other high-value indole-based compounds.
• Bioconjugation & Probe Development: The aldehyde group allows for conjugation with amines, making it useful for creating fluorescent probes or biochemical tags.
• Academic & Institutional R&D: Serves as a standard reagent for teaching and investigating advanced organic reactions involving indole chemistry.

Basic Information

Product Name	1-(3-Dimethylamino-2-Hydroxy-Propyl)-1H-Indole-3-Carbaldehyde
CAS No.	312973-21-0
Molecular Formula	C₁₄H₁₈N₂O₂
Molecular Weight	246.31 g/mol
Synonyms	1H-Indole-3-carboxaldehyde, 1-[3-(dimethylamino)-2-hydroxypropyl]-; 3-Formyl-1-(3-dimethylamino-2-hydroxypropyl)indole; 1-(3-Dimethylamino-2-hydroxypropyl)indole-3-carboxaldehyde; 312973-21-0; 1-(3-Dimethylamino-2-hydroxy-propyl)-1H-indole-3-carbaldehyde; N-[3-(Dimethylamino)-2-hydroxypropyl]indole-3-carboxaldehyde
EINECS	Contact for details

Quality Control

Our 1-(3-Dimethylamino-2-Hydroxy-Propyl)-1H-Indole-3-Carbaldehyde is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specifications such as assay, related substances, and residual solvents are available for every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation and to minimize degradation.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.