Description

Anti-7-Bromo-2-Benzyl-2-Azabicyclo[2.2.1]Heptane CAS NO 312955-00-3 is a specialized, high-purity bicyclic amine derivative, serving as a critical chiral building block and intermediate in advanced organic synthesis. Its unique bridged ring structure and functional groups make it invaluable for constructing complex molecular architectures with precise stereochemistry. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating novel active ingredients and exploring new chemical spaces.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of new active pharmaceutical ingredients (APIs), especially in central nervous system (CNS) and antiviral drug candidates.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and insecticides that require specific stereochemistry for optimal activity.
• Asymmetric Catalysis Ligand Precursor: Serves as a starting material for synthesizing chiral ligands used in asymmetric hydrogenation and other enantioselective transformations.
• Medicinal Chemistry & SAR Studies: Employed in structure-activity relationship (SAR) studies to explore the impact of the rigid bicyclic scaffold on biological activity.
• Academic & Institutional Research: A valuable tool for methodological development in organic synthesis and for teaching advanced concepts in stereochemistry.
• Fine Chemical Synthesis: Used in the multi-step synthesis of complex natural product analogs and other high-value specialty chemicals.

Basic Information

Product Name	Anti-7-Bromo-2-Benzyl-2-Azabicyclo[2.2.1]Heptane
CAS No.	312955-00-3
Molecular Formula	C₁₃H₁₆BrN
Molecular Weight	266.18 g/mol
Synonyms	7-Bromo-2-benzyl-2-azabicyclo[2.2.1]heptane (endo/exo mixture); 2-Benzyl-7-bromo-2-azabicyclo[2.2.1]heptane; 2-Azabicyclo[2.2.1]heptane, 7-bromo-2-(phenylmethyl)-; Anti-7-Bromo-2-Benzyl-2-Azabicycloheptane; Bicyclo[2.2.1]heptane, 7-bromo-2-(phenylmethyl)-2-aza-; 312955-00-3; (1R,2S,4S)-7-Bromo-2-benzyl-2-azabicyclo[2.2.1]heptane (for specific isomer)
EINECS	Contact for details

Quality Control

Every batch of Anti-7-Bromo-2-Benzyl-2-Azabicyclo[2.2.1]Heptane is manufactured under strict quality management systems. We employ advanced analytical techniques, including HPLC, GC, NMR, and chiral analysis, to ensure identity, purity, and enantiomeric/excess specifications are met. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment to guarantee traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% e.e. (for specified isomer)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.