Description

2-Amino-n-(4-Chlorophenyl)-6-Methyl-4,5,6,7-Tetrahydro-1-Benzothiophene-3-Carboxamide is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound matters for its critical role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular scaffolds. Pharmaceutical R&D teams and fine chemical manufacturers need this material for developing next-generation drug candidates, leveraging its specific benzothiophene core for enhanced bioactivity and selectivity.

Application

• Pharmaceutical Intermediate: Primary building block for the synthesis of novel drug candidates, especially in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Research & Development: Essential reference standard and starting material for medicinal chemistry research in academic and industrial laboratories.
• Preclinical Studies: Used in the development and scale-up of lead compounds during early-stage drug discovery programs.
• Custom Synthesis: Serves as a specialized precursor for contract research organizations (CROs) and CDMOs offering bespoke chemical synthesis services.
• Chemical Biology Probes: Utilized in the design of molecular probes to study specific biological pathways and protein interactions.

Basic Information

Product Name	2-Amino-n-(4-Chlorophenyl)-6-Methyl-4,5,6,7-Tetrahydro-1-Benzothiophene-3-Carboxamide
CAS No.	312948-96-2
Molecular Formula	C₁₆H₁₇ClN₂OS
Molecular Weight	320.84 g/mol
Synonyms	2-Amino-N-(4-chlorophenyl)-6-methyl-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide; 2-Amino-6-methyl-N-(4-chlorophenyl)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide; 4,5,6,7-Tetrahydro-2-amino-N-(4-chlorophenyl)-6-methyl-1-benzothiophene-3-carboxamide; CAS 312948-96-2; Benzothiophene-3-carboxamide, 2-amino-N-(4-chlorophenyl)-4,5,6,7-tetrahydro-6-methyl-; 6-Methyl-2-amino-N-(4'-chlorophenyl)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxamide
EINECS	Contact for details

Quality Control

Our production of 2-Amino-n-(4-Chlorophenyl)-6-Methyl-4,5,6,7-Tetrahydro-1-Benzothiophene-3-Carboxamide adheres to stringent quality management systems, ensuring batch-to-batch consistency and high purity essential for pharmaceutical applications. All material is characterized and released against comprehensive specifications, including identity confirmation by spectroscopic methods (IR, NMR) and purity assessment by HPLC. Certificates of Analysis (COA) detailing all test results are provided with each shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.