Description

2-(Piperidin-3-Ylcarbonyl)-1,2,3,4-Tetrahydroisoquinoline is a complex heterocyclic organic compound featuring a tetrahydroisoquinoline scaffold fused with a piperidine carbonyl moiety. This structure makes it a valuable advanced pharmaceutical intermediate and a key building block in medicinal chemistry research. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and biotechnology sectors for the synthesis of novel active pharmaceutical ingredients (APIs) and for lead optimization studies.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Serves as a versatile scaffold for constructing compound libraries in high-throughput screening (HTS) campaigns to identify new biological activities.
• API Development: Used in the process research and development (PR&D) of new chemical entities (NCEs), especially for introducing specific stereochemistry and pharmacophore elements.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes to study enzyme function or receptor interactions in biochemical assays.
• Contract Research & Manufacturing (CRAM): Supplied to CROs and CDMOs engaged in custom synthesis projects for client-specific novel molecules.

Basic Information

Product Name	2-(Piperidin-3-Ylcarbonyl)-1,2,3,4-Tetrahydroisoquinoline
CAS No.	312752-93-5
Molecular Formula	C15H20N2O
Molecular Weight	244.33 g/mol
Synonyms	2-(3-Piperidylcarbonyl)-1,2,3,4-tetrahydroisoquinoline; 1,2,3,4-Tetrahydro-2-[(3-piperidinyl)carbonyl]isoquinoline; 2-(Piperidin-3-carbonyl)-1,2,3,4-tetrahydroisoquinoline; 312752-93-5; UNII-9G1K7I3V8C; 9G1K7I3V8C; AKOS025310947; SCHEMBL15520427; DTXSID60674469
EINECS	Contact for details

Quality Control

Our high-purity pharmaceutical intermediate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided for each lot, supporting your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (typically 15-25°C). The material may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.