Description

3-Amino-4,5,6,7-Tetrahydro-Benzo[B]Thiophene-2-Carboxylic Acid Ethyl Ester is a high-value heterocyclic building block with a fused cyclohexene-thiophene core. This compound matters as a versatile synthon for constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for the synthesis of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, leveraging its heterocyclic structure for biological activity.
• Material Science Research: Serves as a building block for organic electronic materials, such as semiconductors and conductive polymers, due to its electron-rich thiophene moiety.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing specialized compounds for clients.
• Academic Research: Employed in university and institutional labs for methodological development in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	3-Amino-4,5,6,7-Tetrahydro-Benzo[B]Thiophene-2-Carboxylic Acid Ethyl Ester
CAS No.	312697-17-9
Molecular Formula	C11H15NO2S
Molecular Weight	225.31 g/mol
Synonyms	Ethyl 3-Amino-4,5,6,7-tetrahydro-1-benzothiophene-2-carboxylate; 3-Amino-4,5,6,7-tetrahydrobenzo[b]thiophene-2-carboxylic acid ethyl ester; 2-Carbethoxy-3-amino-4,5,6,7-tetrahydrobenzo[b]thiophene; 3-Amino-4,5,6,7-tetrahydro-2-benzothiophenecarboxylic Acid Ethyl Ester; 2-Benzothiophenecarboxylic acid, 3-amino-4,5,6,7-tetrahydro-, ethyl ester; Ethyl 3-amino-4,5,6,7-tetrahydrobenzo[b]thiophene-2-carboxylate
EINECS	Contact for details

Quality Control

Our 3-Amino-4,5,6,7-Tetrahydro-Benzo[B]Thiophene-2-Carboxylic Acid Ethyl Ester is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are available upon request. We can support development projects with material meeting research-grade to GMP-grade standards as required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); the container must be kept tightly sealed to exclude moisture and prevent degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.