Description

Sodium Butyrate-13C4 is a stable isotope-labeled analog of sodium butyrate, where all four carbon atoms are the carbon-13 isotope. This compound is essential for advanced research requiring precise metabolic and pharmacokinetic tracing. It is a critical tool for scientists in pharmaceutical development, nutritional biochemistry, and metabolic disease research who require high-fidelity isotopic labeling for accurate data. The product is supplied under stringent quality control to ensure isotopic and chemical purity for reliable experimental outcomes.

Application

• Isotopic Tracer Studies: Used as a stable isotope-labeled internal standard in quantitative mass spectrometry (MS) and nuclear magnetic resonance (NMR) spectroscopy for precise measurement of butyrate and its metabolites.
• Pharmacokinetics & Drug Metabolism (DMPK): Essential for tracing the absorption, distribution, metabolism, and excretion (ADME) of butyrate-based therapeutics and prodrugs in preclinical research.
• Gut Microbiome & Metabolic Research: Enables detailed investigation of short-chain fatty acid (SCFA) production, utilization, and signaling pathways in cellular and animal models.
• Nutritional Science: Employed in studies examining the role of butyrate in intestinal health, energy metabolism, and as an epigenetic modulator (HDAC inhibitor).
• Analytical Reference Standard: Serves as a certified reference material (CRM) for the calibration of analytical instruments and validation of methods in regulatory and quality control laboratories.
• Biochemical Pathway Elucidation: Facilitates the mapping of metabolic fluxes in central carbon metabolism, particularly in cancer cell biology and immunology research.

Basic Information

Product Name	Sodium Butyrate-13C4
CAS No.	312623-84-0
Molecular Formula	13C4H7NaO2
Molecular Weight	116.07 (based on 13C)
Synonyms	Sodium [13C4]butyrate; Butanoic-13C4 acid, sodium salt; 13C4-Labeled Sodium Butyrate; [13C4]-Sodium Butyrate; Sodium Butyrate (13C4); Isotopically Labeled Sodium Butyrate; Sodium n-Butyrate-13C4; Stable Isotope of Sodium Butyrate
EINECS	Contact for details

Quality Control

Every batch of Sodium Butyrate-13C4 is manufactured and analyzed to meet exacting standards for isotopic enrichment and chemical purity. Our quality assurance protocol includes comprehensive testing via NMR, HPLC, and MS to verify isotopic purity (atom % 13C), chemical assay, and the absence of critical impurities. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting batch-specific results. We support compliance with relevant research and development guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after use to prevent absorption of atmospheric moisture. For long-term storage, consider using a desiccator.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Isotopic Purity (Atom % 13C)	≥ 99%
Chemical Purity (HPLC)	≥ 98.0%
Isotopic Enrichment (MS)	≥ 99% 13C4
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.