Description

5-(2-Fluorophenyl)-4-Phenyl-4H-1,2,4-Triazole-3-Thiol is a specialized heterocyclic compound belonging to the 1,2,4-triazole class, distinguished by its sulfur and fluorine substituents. This compound matters as a versatile and high-value chemical building block and pharmaceutical intermediate, crucial for synthesizing novel active ingredients. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science sectors for developing new drugs, crop protection agents, and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-inflammatory agents, and antimicrobials.
• Agrochemical Research: Serves as a core scaffold for developing new-generation fungicides, herbicides, and plant growth regulators, leveraging its heterocyclic structure.
• Material Science & Coordination Chemistry: Acts as a ligand for metal complexes used in catalysis, luminescent materials, and advanced polymers due to its thiol and nitrogen donor sites.
• Organic Synthesis Building Block: Utilized in medicinal and combinatorial chemistry for constructing complex molecular libraries for high-throughput screening.
• Biochemical Research: Investigated for enzyme inhibition and as a probe in biochemical studies, given its potential to interact with biological thiols.

Basic Information

Product Name	5-(2-Fluorophenyl)-4-Phenyl-4H-1,2,4-Triazole-3-Thiol
CAS No.	311784-46-0
Molecular Formula	C14H10FN3S
Molecular Weight	271.31 g/mol
Synonyms	5-(2-Fluorophenyl)-4-phenyl-4H-1,2,4-triazole-3-thiol; 4-Phenyl-5-(2-fluorophenyl)-2,4-dihydro-3H-1,2,4-triazole-3-thione; 3-Mercapto-5-(2-fluorophenyl)-4-phenyl-1,2,4-triazole; 5-(2-Fluorophenyl)-4-phenyl-1,2,4-triazole-3-thiol; 311784-46-0; 4-Phenyl-5-(o-fluorophenyl)-4H-1,2,4-triazole-3-thiol; 1,2,4-Triazole-3-thiol, 5-(2-fluorophenyl)-4-phenyl-
EINECS	Contact for details

Quality Control

Our 5-(2-Fluorophenyl)-4-Phenyl-4H-1,2,4-Triazole-3-Thiol is produced under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, related substances, and residual solvents. Our quality commitment aligns with cGMP principles where applicable, ensuring reliability for your critical research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is easily oxidized (store under inert atmosphere) and is light-sensitive. Keep away from strong oxidizing agents, strong acids, and strong bases. For long-term storage, consider storing under an inert gas such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.