Description

4-(4-Benzylpiperazino)-1H-Indole Dihydrochloride Monohydrate is a high-purity, non-salt organic compound primarily utilized as a key pharmaceutical intermediate. Its value lies in its role as a critical building block for the synthesis of complex molecules, particularly in medicinal chemistry research and development. This compound is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors, where it is used to develop novel therapeutic agents targeting central nervous system disorders and other conditions.

Application

• Pharmaceutical Intermediate: A crucial precursor in the multi-step synthesis of novel drug candidates, particularly those with indole and piperazine pharmacophores.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and the development of new chemical entities in academic and industrial R&D labs.
• Biochemical Tool Compound: Used in pharmacological assays and as a reference standard to study receptor binding and enzyme inhibition mechanisms.
• API (Active Pharmaceutical Ingredient) Synthesis: Employed in the controlled synthesis of complex active ingredients for preclinical and clinical development phases.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity building blocks.

Basic Information

Product Name	4-(4-Benzylpiperazino)-1H-Indole Dihydrochloride Monohydrate
CAS No.	309755-88-2
Molecular Formula	C19H23Cl2N3O
Molecular Weight	380.31 g/mol
Synonyms	4-(4-Benzylpiperazin-1-yl)-1H-indole dihydrochloride monohydrate; 1H-Indole, 4-(4-benzyl-1-piperazinyl)-, dihydrochloride, monohydrate; 4-(4-Benzylpiperazino)indole dihydrochloride hydrate; 4-(N-Benzylpiperazino)indole dihydrochloride monohydrate; BPI Dihydrochloride Monohydrate
EINECS	Contact for details

Quality Control

Our 4-(4-Benzylpiperazino)-1H-Indole Dihydrochloride Monohydrate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and KF titration for water content, to ensure it meets stringent specifications for pharmaceutical research. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	4.0% - 6.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.