Description

2-Amino-n-(2-Methylphenyl)-5,6,7,8-Tetrahydro-4H-Cyclohepta[B]Thiophene-3-Carboxamide is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular scaffolds. It is primarily sought by research institutions and pharmaceutical manufacturers engaged in drug discovery and development programs.

Application

• Key intermediate in the research and synthesis of novel pharmaceutical compounds.
• Building block for active pharmaceutical ingredients (APIs) targeting central nervous system (CNS) disorders.
• Precursor in medicinal chemistry for the development of potential kinase inhibitors.
• Used in organic synthesis research to construct complex fused-ring systems.
• Starting material for the preparation of specialized chemical libraries for high-throughput screening.
• Critical component in process chemistry development for scale-up to commercial API manufacturing.

Basic Information

Product Name	2-Amino-n-(2-Methylphenyl)-5,6,7,8-Tetrahydro-4H-Cyclohepta[B]Thiophene-3-Carboxamide
CAS No.	309721-14-0
Molecular Formula	C19H22N2OS
Molecular Weight	326.46 g/mol
Synonyms	2-Amino-N-(2-methylphenyl)-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carboxamide; 2-Amino-N-o-tolyl-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide (related fused-ring system); 309721-14-0; Cycloheptathiophene carboxamide derivative; Advanced thiophene intermediate; Pharmaceutical intermediate 309721-14-0; API Intermediate CAS 309721-14-0
EINECS	Contact for details

Quality Control

Our 2-Amino-n-(2-Methylphenyl)-5,6,7,8-Tetrahydro-4H-Cyclohepta[B]Thiophene-3-Carboxamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the stringent requirements for pharmaceutical R&D and process development. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any single impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.