Description

3-(4-Chlorophenyl)-1,5,6,7-Tetrahydro-2H-Cyclopenta[4,5]Thieno[2,3-D]Pyrimidine-2,4(3H)-Dione is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting specific enzymatic pathways. It is primarily sought by research institutions and manufacturers in the pharmaceutical and biotechnology sectors engaged in drug discovery and development programs.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of proprietary drug candidates, especially kinase inhibitors.
• Biochemical Research: Used as a reference standard or a scaffold compound in medicinal chemistry for structure-activity relationship (SAR) studies.
• Organic Synthesis: Serves as a versatile building block for constructing complex fused-ring systems in academic and industrial R&D laboratories.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP production of clinical trial materials.

Basic Information

Product Name	3-(4-Chlorophenyl)-1,5,6,7-Tetrahydro-2H-Cyclopenta[4,5]Thieno[2,3-D]Pyrimidine-2,4(3H)-Dione
CAS No.	309273-77-6
Molecular Formula	C15H11ClN2O2S
Molecular Weight	318.78 g/mol
Synonyms	3-(4-Chlorophenyl)-1,5,6,7-tetrahydro-2H-cyclopenta[4,5]thieno[2,3-d]pyrimidine-2,4(3H)-dione; 3-(p-Chlorophenyl)-1,5,6,7-tetrahydro-2H-cyclopenta[4,5]thieno[2,3-d]pyrimidine-2,4(3H)-dione; Cyclopenta[4,5]thieno[2,3-d]pyrimidine-2,4(3H)-dione, 3-(4-chlorophenyl)-1,5,6,7-tetrahydro-; 309273-77-6; 3-(4-Chlorophenyl)-1,5,6,7-tetrahydro-2H-cyclopenta[4,5]thieno[2,3-d]pyrimidine-2,4-dione
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We provide comprehensive analytical data including HPLC purity, NMR, and MS to verify identity and quality. Certificates of Analysis (COA) are available upon request, and we can support custom synthesis under cGMP guidelines for advanced pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.