Description

S-2,2'-Dihydroxy-α,α,α',α'-Tetraphenyl-[1,1'-Binaphthalene]-3,3'-Dimethanol is a high-value, chiral binaphthol derivative widely recognized as a privileged ligand and catalyst precursor in asymmetric synthesis. Its core value lies in its ability to induce high enantioselectivity in a broad spectrum of organic transformations, making it indispensable for producing optically pure intermediates. This compound is essential for research and production chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require precise stereochemical control.

Application

• Asymmetric Catalysis: Serves as a key chiral ligand for transition metal-catalyzed reactions, including hydrogenation, C-C bond formation, and oxidation.
• Pharmaceutical Intermediates: Critical for the enantioselective synthesis of active pharmaceutical ingredients (APIs) and complex drug molecules.
• Agrochemical Synthesis: Used in the production of chiral pesticides and herbicides to enhance efficacy and reduce environmental impact.
• Material Science: Employed in the development of chiral polymers, liquid crystals, and molecular recognition systems.
• Academic & Industrial R&D: A fundamental building block for methodological development in organic and organometallic chemistry.
• Chiral Resolution: Can be utilized as a resolving agent or as a component of chiral stationary phases for analytical separations.

Basic Information

Product Name	S-2,2'-Dihydroxy-α,α,α',α'-Tetraphenyl-[1,1'-Binaphthalene]-3,3'-Dimethanol
CAS No.	309269-73-6
Molecular Formula	C46H34O4
Molecular Weight	650.76 g/mol
Synonyms	(S)-2,2'-Dihydroxy-1,1'-binaphthyl-3,3'-dimethanol; (S)-3,3'-Bis(hydroxymethyl)-2,2'-dihydroxy-1,1'-binaphthyl; (S)-VAPOL; (S)-3,3'-Bis(hydroxymethyl)-1,1'-bi-2-naphthol; (S)-2,2'-Dihydroxy-3,3'-bis(hydroxymethyl)-1,1'-binaphthyl; (S)-VAPOL ligand; (S)-VAPOL alcohol; (S)-VAPOL precursor
EINECS	Contact for details

Quality Control

Our S-2,2'-Dihydroxy-α,α,α',α'-Tetraphenyl-[1,1'-Binaphthalene]-3,3'-Dimethanol is manufactured under strict quality protocols to ensure batch-to-batch consistency and high enantiomeric purity. All products undergo rigorous analytical testing, including HPLC, NMR, and optical rotation measurement, to confirm identity, purity, and chiral integrity. Certificates of Analysis (COA) detailing all specifications are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Keep the container sealed in a dry, inert atmosphere to prevent moisture absorption and oxidation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.