Description

2-(7-Amino-1-Isoquinolinyl)Imidodicarbonic Acid 1,3-Bis(1,1-Dimethylethyl) Ester is a high-purity, protected amino-isoquinoline derivative serving as a critical building block in advanced organic synthesis. Its primary value lies in providing a reactive amino group that is temporarily shielded by the Boc (tert-butoxycarbonyl) protecting group, enabling precise and sequential chemical transformations. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and complex heterocyclic molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, especially those targeting kinases and other enzymes where the isoquinoline scaffold is pharmacologically relevant.
• Agrochemical Research: Used in developing new pesticides and herbicides, leveraging its heterocyclic structure for bioactivity.
• Organic Synthesis Building Block: Employed in multi-step synthetic routes to construct complex nitrogen-containing heterocycles for material science and chemical biology.
• Peptidomimetics & PROTACs: Serves as a component in the design of peptide mimics and Proteolysis-Targeting Chimeras (PROTACs) due to its protected amine functionality.
• Chemical Biology Probes: Utilized in the creation of labeled probes and molecular tools for studying biological pathways and protein interactions.

Basic Information

Product Name	2-(7-Amino-1-Isoquinolinyl)Imidodicarbonic Acid 1,3-Bis(1,1-Dimethylethyl) Ester
CAS No.	309263-17-0
Molecular Formula	C21H27N3O4
Molecular Weight	385.46 g/mol
Synonyms	7-Amino-1-isoquinolinecarboxylic acid 1,1-dimethylethyl ester; 2-(7-Amino-1-isoquinolinyl)-1H-imidazole-1,3(2H)-dione, 1,3-bis(1,1-dimethylethyl) ester; 7-Amino-1-isoquinoline N-Boc derivative; tert-Butyl (7-amino-1-isoquinolyl)imidodicarbonate; Boc-Protected 7-Aminoisoquinoline; 309263-17-0; 2-(7-Amino-isoquinolin-1-yl)-imidodicarbonic acid di-tert-butyl ester
EINECS	Contact for details

Quality Control

Our 2-(7-Amino-1-Isoquinolinyl)Imidodicarbonic Acid 1,3-Bis(1,1-Dimethylethyl) Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our commitment to quality supports research and development requiring high-purity, well-characterized building blocks for critical synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic); ensure the container is sealed under an inert atmosphere after each use to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.