Description

Ethyl (2E)-4-[(5-Benzyl-3-Carbamoyl-4-Methylthiophen-2-Yl)Amino]-4-Oxobut-2-Enoate is a high-purity, advanced pharmaceutical intermediate characterized by its specific thiophene-based molecular architecture. This compound matters for its role as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), where precise chemical structure is paramount for biological activity. It is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing new therapeutic agents and specialty chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of novel drug candidates, particularly those targeting specific enzymatic pathways.
• API Synthesis: Used in the multi-step synthesis of complex Active Pharmaceutical Ingredients (APIs) requiring a defined thiophene moiety.
• Agrochemical Research: Acts as a precursor in the development of new generation pesticides and herbicides with tailored activity profiles.
• Chemical Biology Probes: Utilized in the creation of specialized molecular probes for studying biological processes and target identification.
• Organic Synthesis Building Block: Provides a versatile scaffold for medicinal chemists to create libraries of compounds for high-throughput screening.

Basic Information

Product Name	Ethyl (2E)-4-[(5-Benzyl-3-Carbamoyl-4-Methylthiophen-2-Yl)Amino]-4-Oxobut-2-Enoate
CAS No.	308293-39-2
Molecular Formula	C20H22N2O4S
Molecular Weight	386.47 g/mol
Synonyms	Ethyl (2E)-4-[(5-benzyl-3-carbamoyl-4-methyl-2-thienyl)amino]-4-oxo-2-butenoate; 2-Butenoic acid, 4-[(5-benzyl-3-carbamoyl-4-methyl-2-thienyl)amino]-4-oxo-, ethyl ester, (2E)-; Ethyl 4-[(5-Benzyl-3-Carbamoyl-4-Methyl-2-Thienyl)Amino]-4-Oxo-2-butenoate; (2E)-Ethyl 4-((5-benzyl-3-carbamoyl-4-methylthiophen-2-yl)amino)-4-oxobut-2-enoate; CAS 308293-39-2
EINECS	Contact for details

Quality Control

Our Ethyl (2E)-4-[(5-Benzyl-3-Carbamoyl-4-Methylthiophen-2-Yl)Amino]-4-Oxobut-2-Enoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) detailing batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.