Description

Ethyl 2-(2-Fluorobenzamido)-5,6-Dihydro-4H-Cyclopenta[B]Thiophene-3-Carboxylate is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of complex active pharmaceutical ingredients (APIs). This compound is critical for research and development programs targeting novel therapeutic agents, particularly in areas requiring specific molecular scaffolds. It is primarily utilized by pharmaceutical manufacturers, contract research organizations (CROs), and fine chemical synthesis specialists.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, especially those with fused cyclopentathiophene cores.
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• API Synthesis: Serves as a precursor in multi-step synthetic routes for target molecules in pre-clinical and clinical development.
• Chemical Reference Standard: Employed as an analytical standard for quality control and method validation in pharmaceutical analysis.
• Custom Synthesis: Starting material for the preparation of specialized derivatives and analogs for biological screening.

Basic Information

Product Name	Ethyl 2-(2-Fluorobenzamido)-5,6-Dihydro-4H-Cyclopenta[B]Thiophene-3-Carboxylate
CAS No.	307536-69-2
Molecular Formula	C17H16FNO3S
Molecular Weight	333.38 g/mol
Synonyms	Ethyl 2-[(2-fluorobenzoyl)amino]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate; 2-(2-Fluorobenzamido)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylic Acid Ethyl Ester; 307536-69-2; 2-[(2-Fluorobenzoyl)amino]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylic Acid Ethyl Ester; Ethyl 2-[(2-fluorophenyl)carbonylamino]-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxylate
EINECS	Contact for details

Quality Control

Our Ethyl 2-(2-Fluorobenzamido)-5,6-Dihydro-4H-Cyclopenta[B]Thiophene-3-Carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the stringent requirements for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.