Description

Ethyl 2-Amino-4-[1,1'-Biphenyl]-4-Yl-3-Thiophenecarboxylate is a high-purity, specialized organic intermediate featuring a biphenyl-thiophene core structure. This compound is valued for its role as a critical building block in advanced pharmaceutical and materials science research. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and organic electronics industries for synthesizing novel active compounds and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Research: Used in developing new active ingredients for crop protection agents, leveraging its complex heterocyclic structure.
• Organic Electronic Materials: Serves as a building block for organic semiconductors, hole-transport materials, and light-emitting diodes (OLEDs) due to its conjugated biphenyl-thiophene system.
• Ligand Synthesis: Utilized in organometallic chemistry for creating specialized ligands used in catalysis.
• Fluorescent Probe Development: Acts as a core structure for synthesizing advanced fluorescent dyes and molecular probes for bio-imaging.
• Academic & Industrial R&D: Essential for exploratory chemistry in universities and corporate research centers focusing on novel heterocyclic compounds.

Basic Information

Product Name	Ethyl 2-Amino-4-[1,1'-Biphenyl]-4-Yl-3-Thiophenecarboxylate
CAS No.	307343-50-6
Molecular Formula	C25H21NO2S
Molecular Weight	399.50 g/mol
Synonyms	Ethyl 2-Amino-4-(biphenyl-4-yl)thiophene-3-carboxylate; 2-Amino-4-(4-phenylphenyl)-3-thiophenecarboxylic Acid Ethyl Ester; 4-(1,1'-Biphenyl-4-yl)-2-amino-3-thiophenecarboxylic Acid Ethyl Ester; 307343-50-6; Ethyl 2-amino-4-(4-phenylphenyl)thiophene-3-carboxylate; AKOS BRN-0791; BRN 0791; 4-[1,1'-Biphenyl]-4-yl-2-amino-3-thiophenecarboxylic acid ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 2-Amino-4-[1,1'-Biphenyl]-4-Yl-3-Thiophenecarboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable performance in your sensitive synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.