Description

Methyl 5-Benzyl-4-Methyl-2-[(Trifluoroacetyl)Amino]Thiophene-3-Carboxylate is a high-value, multi-functional heterocyclic building block designed for advanced synthetic chemistry. This compound matters for its role as a critical intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its unique thiophene scaffold and trifluoroacetyl-protected amine group enable precise molecular construction. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and specialty fine chemical industries seeking to create new molecules with targeted properties.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-inflammatory agents, and other therapeutic areas.
• Agrochemical Research: Serves as a building block for developing new generation herbicides, fungicides, and insecticides with improved efficacy and selectivity.
• Material Science: Used in the research and development of advanced organic electronic materials, such as organic semiconductors and conductive polymers.
• Chemical Biology & Proteomics: Can be utilized as a specialized reagent or linker in probe development for studying biological systems and protein interactions.
• Custom Synthesis & Contract Manufacturing: An essential starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing complex molecules for clients.
• Academic & Institutional Research: Employed in university and institutional labs for methodological development in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	Methyl 5-Benzyl-4-Methyl-2-[(Trifluoroacetyl)Amino]Thiophene-3-Carboxylate
CAS No.	307340-42-7
Molecular Formula	C16H14F3NO3S
Molecular Weight	357.35 g/mol
Synonyms	Methyl 2-[(2,2,2-trifluoroacetyl)amino]-5-benzyl-4-methylthiophene-3-carboxylate; 5-Benzyl-4-methyl-2-[(trifluoroacetyl)amino]thiophene-3-carboxylic acid methyl ester; Methyl 5-benzyl-4-methyl-2-(trifluoroacetamido)thiophene-3-carboxylate; 2-(Trifluoroacetamido)-5-benzyl-4-methylthiophene-3-carboxylic acid methyl ester; 307340-42-7; Thiophene-3-carboxylic acid, 2-[(2,2,2-trifluoroacetyl)amino]-5-(phenylmethyl)-4-methyl-, methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 5-Benzyl-4-Methyl-2-[(Trifluoroacetyl)Amino]Thiophene-3-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our commitment to quality supports your R&D and scale-up processes with reliable, high-purity material.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.