Description

4-(4-Chloro-Phenyl)-1-(2-Methoxy-Phenyl)-1H-Imidazole-2-Thiol is a high-purity, functionalized imidazole derivative of significant interest in advanced organic synthesis. This compound matters as a versatile and critical building block for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for creating new molecules with targeted biological activities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Research: Serves as a core scaffold for developing new-generation fungicides, herbicides, and plant growth regulators with improved efficacy and selectivity.
• Ligand Synthesis: Used in coordination chemistry to create specialized ligands for catalytic systems and metal-organic frameworks (MOFs).
• Material Science: Employed in the research and development of advanced organic electronic materials and functional polymers.
• Biochemical Probe Development: Utilized as a starting material for synthesizing molecular probes to study enzyme mechanisms and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds for client R&D projects.

Basic Information

Product Name	4-(4-Chloro-Phenyl)-1-(2-Methoxy-Phenyl)-1H-Imidazole-2-Thiol
CAS No.	307325-50-4
Molecular Formula	C16H13ClN2OS
Molecular Weight	316.80 g/mol
Synonyms	4-(4-Chlorophenyl)-1-(2-methoxyphenyl)-1H-imidazole-2-thiol; 1-(2-Methoxyphenyl)-4-(4-chlorophenyl)-1H-imidazole-2-thiol; 2-Mercapto-4-(4-chlorophenyl)-1-(2-methoxyphenyl)imidazole; 4-(p-Chlorophenyl)-1-(o-methoxyphenyl)imidazole-2-thiol; CAS 307325-50-4; Imidazole-2-thiol derivative (4-chloro, 2-methoxy phenyl substituted)
EINECS	Contact for details

Quality Control

Our 4-(4-Chloro-Phenyl)-1-(2-Methoxy-Phenyl)-1H-Imidazole-2-Thiol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding synthesis projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized; for long-term storage, consider keeping under an inert atmosphere such as nitrogen or argon. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.