Description

(E)-n-(5-Bromo-2-Oxoindolin-3-Ylidene)-3-(4-Ethoxyphenyl)-1H-Pyrazole-5-Carbohydrazide is a high-purity, synthetically valuable heterocyclic organic compound featuring a complex indolinone-pyrazole hybrid structure. This compound matters as a critical pharmaceutical intermediate and a versatile chemical building block for advanced research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of novel active molecules.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug candidates, particularly those targeting kinase inhibition or other biological pathways.
• Chemical Research & Development: Used as a sophisticated building block for constructing complex heterocyclic libraries for high-throughput screening and structure-activity relationship (SAR) studies.
• Agrochemical Synthesis: Employed in the research and development of novel herbicides, fungicides, or insecticides due to its bioactive scaffold.
• Material Science Research: Investigated as an organic component for advanced materials, such as organic semiconductors or photoactive compounds.
• Reference Standard: Supplied as a high-purity analytical standard for quality control and method development in analytical laboratories.
• Academic Research: Utilized in universities and research institutes for studies in organic synthesis methodology and medicinal chemistry.

Basic Information

Product Name	(E)-n-(5-Bromo-2-Oxoindolin-3-Ylidene)-3-(4-Ethoxyphenyl)-1H-Pyrazole-5-Carbohydrazide
CAS No.	306987-58-6
Molecular Formula	C20H16BrN5O3
Molecular Weight	454.28 g/mol
Synonyms	5-Bromo-3-[(E)-[5-(2-[(4-ethoxyphenyl)carbonyl]hydrazinyl)-1H-pyrazol-3-yl]methylene]-1,3-dihydro-2H-indol-2-one; (E)-N'-(5-Bromo-2-oxoindolin-3-ylidene)-3-(4-ethoxyphenyl)-1H-pyrazole-5-carbohydrazide; 3-(4-Ethoxyphenyl)-1H-pyrazole-5-carboxylic acid (5-bromo-2-oxo-2,3-dihydro-1H-indol-3-ylidene)hydrazide; 5-Bromo-3-((5-(2-(4-ethoxybenzoyl)hydrazineyl)-1H-pyrazol-3-yl)methylene)indolin-2-one; 306987-58-6; BRD-K4477 (common research code)
EINECS	Contact for details

Quality Control

Our (E)-n-(5-Bromo-2-Oxoindolin-3-Ylidene)-3-(4-Ethoxyphenyl)-1H-Pyrazole-5-Carbohydrazide is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications and test results are provided and available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	Yellow to orange powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.