Description

2-Mercapto-4-(Trifluoromethyl)-5,6,7,8-Tetrahydroquinoline-3-Carbonitrile is a high-value, multi-functional heterocyclic building block characterized by its unique trifluoromethyl and nitrile substituents. This compound matters for its critical role in modern pharmaceutical and agrochemical research, where it serves as a versatile precursor for synthesizing novel active ingredients. Industrial chemists and R&D professionals in the pharmaceutical, crop protection, and advanced materials sectors need this intermediate to develop new compounds with enhanced biological activity and physical properties.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in therapeutic areas targeting the central nervous system, oncology, and infectious diseases.
• Agrochemical Synthesis: Used in the research and production of next-generation pesticides and herbicides, where the trifluoromethyl group can improve metabolic stability and bioavailability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in catalysis and metal-organic frameworks (MOFs) due to its sulfur and nitrogen donor atoms.
• Material Science Research: Investigated for the synthesis of advanced organic electronic materials and functional polymers.
• Chemical Biology Probes: Utilized in the design of molecular probes and inhibitors for studying enzyme function and biological pathways.

Basic Information

Product Name	2-Mercapto-4-(Trifluoromethyl)-5,6,7,8-Tetrahydroquinoline-3-Carbonitrile
CAS No.	306935-92-2
Molecular Formula	C11H9F3N2S
Molecular Weight	258.26 g/mol
Synonyms	4-(Trifluoromethyl)-5,6,7,8-tetrahydroquinoline-3-carbonitrile-2-thiol; 2-Mercapto-4-trifluoromethyl-5,6,7,8-tetrahydroquinoline-3-carbonitrile; 2-Thioxo-1,2-dihydro-4-(trifluoromethyl)-5,6,7,8-tetrahydroquinoline-3-carbonitrile; 4-(Trifluoromethyl)-2-mercapto-5,6,7,8-tetrahydroquinoline-3-carbonitrile; 306935-92-2; THQ derivative; Tetrahydroquinoline-3-carbonitrile intermediate
EINECS	Contact for details

Quality Control

Our 2-Mercapto-4-(Trifluoromethyl)-5,6,7,8-Tetrahydroquinoline-3-Carbonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and LC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are available upon request, supporting your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to handle and store under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.