Description

4-Benzyl-5-(n-tert-Butoxycarbonylaminomethyl)-1,2,4-Triazole-3-Thiol is a specialized heterocyclic compound featuring a protected amine group and a thiol functionality. This unique structure makes it a valuable building block and intermediate in advanced organic synthesis, particularly for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily sought by research institutions and manufacturers in the pharmaceutical and fine chemical industries for drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting specific enzyme inhibition.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators.
• Peptidomimetics Synthesis: Serves as a constrained scaffold or side-chain component in the design of peptide-like molecules with enhanced stability.
• Ligand Development: Utilized in medicinal chemistry for creating chelating agents or ligands in catalytic systems.
• Chemical Biology Probes: Acts as a precursor for probes used to study biological pathways and protein interactions.
• Material Science Research: Investigated as a monomer or additive for creating polymers with specific functional properties.

Basic Information

Product Name	4-Benzyl-5-(n-tert-Butoxycarbonylaminomethyl)-1,2,4-Triazole-3-Thiol
CAS No.	306935-43-3
Molecular Formula	C16H22N4O2S
Molecular Weight	334.44 g/mol
Synonyms	Boc-AMT; 5-[[(tert-Butoxycarbonyl)amino]methyl]-4-benzyl-4H-1,2,4-triazole-3-thiol; 4-Benzyl-5-[(tert-butoxycarbonylamino)methyl]-2,4-dihydro-3H-1,2,4-triazole-3-thione; 4-Benzyl-5-[(tert-butoxycarbonylamino)methyl]-1,2,4-triazole-3-thiol; 3H-1,2,4-Triazole-3-thione, 5-[[[(1,1-dimethylethoxy)carbonyl]amino]methyl]-4-(phenylmethyl)-; 4-Benzyl-5-(Boc-aminomethyl)-1,2,4-triazole-3-thiol; tert-Butyl N-[(4-benzyl-3-sulfanyl-4H-1,2,4-triazol-5-yl)methyl]carbamate
EINECS	Contact for details

Quality Control

Our 4-Benzyl-5-(n-tert-Butoxycarbonylaminomethyl)-1,2,4-Triazole-3-Thiol is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and structural identity. Certificates of Analysis (COA) detailing purity, impurities, and other critical parameters are provided with every shipment to guarantee batch-to-batch consistency for your research and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is easily oxidized; for long-term storage, consider keeping the container under an inert atmosphere such as nitrogen or argon to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.