Description

Methyl 3-Chloro-4-(Isopropylsulfonyl)-5-(Methylthio)Thiophene-2-Carboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its unique thiophene core with sulfonyl and thioether functional groups. This compound is of significant commercial value for its role in the synthesis of complex active pharmaceutical ingredients (APIs), particularly in agrochemical and pharmaceutical research. It is primarily sought by R&D chemists and process development scientists in the fine chemical and agrochemical manufacturing sectors for constructing novel molecular architectures.

Application

• Key Intermediate in Agrochemical Synthesis: Serves as a critical building block for the development of new-generation herbicides and fungicides, leveraging the bioactivity of the functionalized thiophene ring.
• Pharmaceutical Intermediate: Used in the research and scale-up production of potential drug candidates, especially those targeting specific enzyme pathways where the sulfonyl group acts as a key pharmacophore.
• Organic Synthesis Building Block: Employed in academic and industrial laboratories for the construction of complex heterocyclic compounds and for studying novel organic reactions involving sulfones and thioethers.
• Material Science Research: Investigated as a precursor for specialty polymers or organic electronic materials due to the conjugated nature of the thiophene system.

Basic Information

Product Name	Methyl 3-Chloro-4-(Isopropylsulfonyl)-5-(Methylthio)Thiophene-2-Carboxylate
CAS No.	306935-21-7
Molecular Formula	C10H13ClO4S3
Molecular Weight	328.85 g/mol
Synonyms	Methyl 3-chloro-4-(isopropylsulfonyl)-5-(methylthio)thiophene-2-carboxylate; 3-Chloro-4-(isopropylsulfonyl)-5-(methylthio)thiophene-2-carboxylic acid methyl ester; Thiophene-2-carboxylic acid, 3-chloro-4-[(1-methylethyl)sulfonyl]-5-(methylthio)-, methyl ester; Methyl 3-chloro-5-(methylthio)-4-[(propan-2-yl)sulfonyl]thiophene-2-carboxylate; CAS 306935-21-7
EINECS	Contact for details

Quality Control

Every batch of Methyl 3-Chloro-4-(Isopropylsulfonyl)-5-(Methylthio)Thiophene-2-Carboxylate is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency meet the stringent requirements of our clients in pharmaceutical development. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical characteristics is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.