Description

3-Amino-5-[4-(tert-Butyl)Phenyl]Thiophene-2-Carboxamide is a high-value, multi-functional heterocyclic building block featuring a thiophene core with both amino and carboxamide substituents. This compound is critical for the synthesis of advanced materials and active pharmaceutical ingredients (APIs) due to its unique electronic properties and structural versatility. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and organic electronics sectors for developing novel compounds with targeted functionalities.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Synthesis: Used in the research and development of new-generation pesticides and herbicides, leveraging its heterocyclic structure for bioactivity.
• Organic Electronic Materials: Acts as a building block for conjugated polymers and small molecules used in organic light-emitting diodes (OLEDs) and organic photovoltaics (OPVs).
• Chemical Research & Development: Employed as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Dye and Pigment Intermediate: Utilized in the development of specialized dyes and pigments due to the chromophoric thiophene system.
• Ligand for Catalysis: Can be functionalized to create novel ligands for transition metal catalysts used in cross-coupling reactions.

Basic Information

Product Name	3-Amino-5-[4-(tert-Butyl)Phenyl]Thiophene-2-Carboxamide
CAS No.	306935-13-7
Molecular Formula	C15H18N2OS
Molecular Weight	274.38 g/mol
Synonyms	3-Amino-5-(4-tert-butylphenyl)thiophene-2-carboxamide; 5-(4-tert-Butylphenyl)-3-aminothiophene-2-carboxamide; 2-Carbamoyl-5-(4-tert-butylphenyl)thiophen-3-amine; 306935-13-7; AKOS BRN 0973; 3-Amino-5-(p-tert-butylphenyl)thiophene-2-carboxamide; Thiophene-2-carboxamide, 3-amino-5-[4-(1,1-dimethylethyl)phenyl]-
EINECS	Contact for details

Quality Control

Our 3-Amino-5-[4-(tert-Butyl)Phenyl]Thiophene-2-Carboxamide is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC purity, NMR, and mass spectrometry confirmation. A Certificate of Analysis (COA) is supplied with each batch, detailing all relevant specifications. Our quality management system is designed to meet the stringent requirements of research and development as well as scale-up production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.