Description

3-[(3-Iodo-4-Methylphenyl)Imino]-1,3-Dihydro-2H-Indol-2-One is a high-purity, specialized organic compound belonging to the indolinone class. This compound serves as a critical synthetic intermediate and building block in advanced pharmaceutical and agrochemical research. It is primarily required by R&D chemists and process development scientists working in medicinal chemistry, particularly for the synthesis of novel bioactive molecules and heterocyclic compounds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, especially kinase inhibitors and other targeted therapies.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes due to its unique halogenated and imino-indolinone structure.
• Agrochemical Development: Intermediate in the research and synthesis of novel pesticides and herbicides.
• Organic Synthesis: Versatile precursor for constructing complex heterocyclic frameworks and for introducing the iodomethylphenyl moiety into target molecules.
• Chemical Biology Probes: Potential use in the development of molecular probes for studying biological pathways and protein interactions.
• Material Science Research: Investigated as a monomer or precursor for specialty polymers and advanced organic materials.

Basic Information

Product Name	3-[(3-Iodo-4-Methylphenyl)Imino]-1,3-Dihydro-2H-Indol-2-One
CAS No.	306325-04-2
Molecular Formula	C15H11IN2O
Molecular Weight	362.17 g/mol
Synonyms	3-[(3-Iodo-4-methylphenyl)imino]indolin-2-one; 2H-Indol-2-one, 1,3-dihydro-3-[(3-iodo-4-methylphenyl)imino]-; 3-(3-Iodo-4-methylphenylimino)indolin-2-one; 3-[(3-Iodo-p-tolyl)imino]-1,3-dihydro-2H-indol-2-one; (Z)-3-((3-Iodo-4-methylphenyl)imino)indolin-2-one; Isatin 3-(3-iodo-4-methylphenyl)imine; 306325-04-2
EINECS	Contact for details

Quality Control

Our 3-[(3-Iodo-4-Methylphenyl)Imino]-1,3-Dihydro-2H-Indol-2-One is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, suitable for demanding research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable, and our quality systems are designed to meet the stringent requirements of pharmaceutical R&D.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at a controlled room temperature (15-25°C). This compound is light-sensitive and easily oxidized; prolonged exposure to air, light, or moisture should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.