Description

5-(2-Methyl-Propane-2-Sulfonyl)-Thiophene-2-Carboxylic Acid is a high-purity, functionalized heterocyclic building block of significant interest in advanced organic synthesis. This compound is valued for its unique molecular architecture, which combines a thiophene carboxylic acid moiety with a tert-butyl sulfonyl group, enabling precise chemical modifications. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of new drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the thiophene-sulfonyl motif can contribute to enhanced biological activity.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the creation of specialty polymers and organic electronic materials.
• Chemical Research: Employed in academic and industrial R&D for method development, catalysis studies, and the exploration of novel sulfone and heterocycle chemistry.
• Ligand and Catalyst Design: The carboxylic acid and sulfonyl groups make it a useful precursor for designing complex ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	5-(2-Methyl-Propane-2-Sulfonyl)-Thiophene-2-Carboxylic Acid
CAS No.	306293-86-7
Molecular Formula	C9H12O4S2
Molecular Weight	248.32 g/mol
Synonyms	2-Thiophenecarboxylic acid, 5-[(1,1-dimethylethyl)sulfonyl]-; 5-(tert-Butylsulfonyl)thiophene-2-carboxylic acid; 5-(tert-Butylsulfonyl)-2-thiophenecarboxylic acid; 5-(2-Methyl-2-propanesulfonyl)thiophene-2-carboxylic acid; 5-(tert-Butanesulfonyl)thiophene-2-carboxylic acid; 5-(t-Butylsulfonyl)thiophene-2-carboxylic acid; 306293-86-7
EINECS	Contact for details

Quality Control

Our 5-(2-Methyl-Propane-2-Sulfonyl)-Thiophene-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals to ensure it meets the stringent requirements of research and process development. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.