Description

Ethyl 2-(Furan-2-Carboxamido)-4-(p-Tolyl)Thiophene-3-Carboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its unique heterocyclic structure combining furan and thiophene moieties. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D laboratories, agrochemical innovators, and specialty chemical manufacturers seeking to develop new therapeutic agents or functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammatory diseases, or as kinase inhibitors.
• Agrochemical Research: Used in the development of new generation pesticides and herbicides, leveraging its heterocyclic scaffold for bioactivity.
• Material Science Precursor: Acts as a monomer or precursor for the development of organic semiconductors, conductive polymers, or specialty dyes and pigments.
• Academic & Contract Research: Essential for university laboratories and CROs (Contract Research Organizations) conducting structure-activity relationship (SAR) studies and medicinal chemistry programs.
• Process Chemistry Development: Employed in scaling up synthetic routes from milligram to kilogram scale for pre-clinical and clinical trial material supply.

Basic Information

Product Name	Ethyl 2-(Furan-2-Carboxamido)-4-(p-Tolyl)Thiophene-3-Carboxylate
CAS No.	306281-00-5
Molecular Formula	C19H17NO4S
Molecular Weight	355.41 g/mol
Synonyms	Ethyl 2-[(furan-2-carbonyl)amino]-4-(4-methylphenyl)thiophene-3-carboxylate; 2-(Furan-2-carboxamido)-4-(p-tolyl)thiophene-3-carboxylic acid ethyl ester; 4-(4-Methylphenyl)-2-[(2-furoyl)amino]thiophene-3-carboxylic acid ethyl ester; Ethyl 4-(4-methylphenyl)-2-[(2-furoyl)amino]thiophene-3-carboxylate; Furan-2-carboxylic acid [3-(ethoxycarbonyl)-4-(4-methylphenyl)thiophen-2-yl]amide; CAS 306281-00-5
EINECS	Contact for details

Quality Control

Our Ethyl 2-(Furan-2-Carboxamido)-4-(p-Tolyl)Thiophene-3-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and Mass Spectrometry, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider inert atmosphere conditions to ensure stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.