Description

2-(2-Chloro-Acetylamino)-4-(4-Fluoro-Phenyl)-Thiophene-3-Carboxylic Acid Ethyl Ester is a high-purity, advanced pharmaceutical intermediate with a defined molecular structure. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers targeting therapeutic areas where thiophene-based scaffolds are of significant interest.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders, inflammation, or oncology.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes to develop new therapeutic agents.
• Active Pharmaceutical Ingredient (API) Synthesis: Serves as a precursor in multi-step synthetic routes for the production of complex, target-specific APIs.
• Chemical Reference Standard: Employed as an analytical standard for quality control and method development in pharmaceutical analysis.
• Organic Synthesis: Utilized in academic and industrial research for exploring new heterocyclic chemistry and developing novel synthetic methodologies.

Basic Information

Product Name	2-(2-Chloro-Acetylamino)-4-(4-Fluoro-Phenyl)-Thiophene-3-Carboxylic Acid Ethyl Ester
CAS No.	306280-84-2
Molecular Formula	C15H13ClFNO3S
Molecular Weight	341.78 g/mol
Synonyms	Ethyl 2-[(2-chloroacetyl)amino]-4-(4-fluorophenyl)thiophene-3-carboxylate; 2-(2-Chloroacetamido)-4-(4-fluorophenyl)thiophene-3-carboxylic acid ethyl ester; 4-(4-Fluorophenyl)-2-[(2-chloroacetyl)amino]thiophene-3-carboxylic acid ethyl ester; 306280-84-2; AKOS BRN 0979; Thiophene-3-carboxylic acid, 2-[(2-chloroacetyl)amino]-4-(4-fluorophenyl)-, ethyl ester
EINECS	Contact for details

Quality Control

Our 2-(2-Chloro-Acetylamino)-4-(4-Fluoro-Phenyl)-Thiophene-3-Carboxylic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.