Description

4-[(5Z)-4-Oxo-5-(2-Oxo-1,2-Dihydro-3H-Indol-3-Ylidene)-2-Thioxo-1,3-Thiazolidin-3-Yl]Benzoic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel therapeutic agents targeting specific biological pathways. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the development of innovative drug candidates.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel small-molecule drug candidates, particularly those with indole and thiazolidinone pharmacophores.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for developing new therapeutic agents.
• Biochemical Probe Development: Serves as a core structure for creating probes to study enzyme inhibition and protein-ligand interactions.
• Organic Synthesis Reference Standard: Employed as a high-purity standard for analytical method development and validation in QC laboratories.
• Academic Research: Utilized in university and institutional labs for investigating heterocyclic chemistry and new synthetic methodologies.

Basic Information

Product Name	4-[(5Z)-4-Oxo-5-(2-Oxo-1,2-Dihydro-3H-Indol-3-Ylidene)-2-Thioxo-1,3-Thiazolidin-3-Yl]Benzoic Acid
CAS No.	305376-86-7
Molecular Formula	C18H10N2O4S2
Molecular Weight	382.41 g/mol
Synonyms	4-[(5Z)-5-(2-Oxo-1,2-dihydro-3H-indol-3-ylidene)-4-oxo-2-thioxo-1,3-thiazolidin-3-yl]benzoic acid; 3-[3-(4-Carboxyphenyl)-4-oxo-2-thioxo-1,3-thiazolidin-5-ylidene]indolin-2-one; (5Z)-3-(4-Carboxyphenyl)-5-(2-oxo-1,2-dihydro-3H-indol-3-ylidene)-2-thioxo-1,3-thiazolidin-4-one; 4-(5Z)-5-(2-Oxo-1,2-dihydroindol-3-ylidene)-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-ylbenzoic acid; Benzoic acid, 4-[(5Z)-4-oxo-5-(2-oxo-1,2-dihydro-3H-indol-3-ylidene)-2-thioxo-1,3-thiazolidin-3-yl]-
EINECS	Contact for details

Quality Control

Our 4-[(5Z)-4-Oxo-5-(2-Oxo-1,2-Dihydro-3H-Indol-3-Ylidene)-2-Thioxo-1,3-Thiazolidin-3-Yl]Benzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Yellow to orange powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.