Description

5-Bromo-3-Ethyl-1,3-Dihydro-Indol-2-One is a high-purity brominated oxindole derivative, a crucial advanced intermediate in modern organic synthesis. Its value lies in its versatile reactivity, serving as a key building block for constructing complex heterocyclic frameworks with potential biological activity. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, particularly those exploring kinase inhibitors and other small molecule therapeutics.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of complex drug candidates, especially those targeting kinase pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators.
• Organic Synthesis Building Block: Employed in medicinal chemistry for constructing indole and oxindole-based compound libraries for high-throughput screening.
• Biochemical Research: Serves as a reference standard or a starting material for probes and inhibitors used in biochemical assays.
• Material Science Research: Potential precursor for specialty polymers or organic electronic materials due to its heterocyclic structure.

Basic Information

Product Name	5-Bromo-3-Ethyl-1,3-Dihydro-Indol-2-One
CAS No.	304876-05-9
Molecular Formula	C10H10BrNO
Molecular Weight	240.10 g/mol
Synonyms	5-Bromo-3-ethylindolin-2-one; 3-Ethyl-5-bromo-1,3-dihydro-2H-indol-2-one; 5-Bromo-3-ethyl-2-indolinone; 2H-Indol-2-one, 5-bromo-1,3-dihydro-3-ethyl-; 5-Bromo-3-ethyloxindole; 304876-05-9; 5-Br-3-Et-oxindole
EINECS	Contact for details

Quality Control

Our 5-Bromo-3-Ethyl-1,3-Dihydro-Indol-2-One is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical research and development processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storage under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.